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An evaluation of the prevalence, characteristics, outcomes and predictors of shock in children admitted to paediatric wards at Queen Elizabeth Central Hospital in Blantyre, Malawi

Kumwenda, Mercy (Kamuzu University of Health Sciences, 2021-06-01)

Shock is an important pathophysiological mechanism of death in children in low-resource settings. Despite this, limited data is available on the prevalence, causes and outcome of shock in children in these settings. We ...
Psychosocial care for road traffic injury patients: An exploration of service provision to patients attending Orthopaedic Clinic at Queen Elizabeth Central Hospital in Blantyre, Malawi

Chigalu Chingwalu, Maclean Grace (Kamuzu University of Health Sciences, 2022-03-30)

Every year the lives of approximately 1.35 million people globally, are cut short as a result of a road traffic crash. Road traffic accidents are responsible for different types of injuries and disabilities which affect ...
Hypertension service delivery capacity assessment in Malawi: Results from Malawi longitudinal study of families and health in Balaka, Machinga, Mchinji and Rumphi health care facilities

Mbulaje, Lucia Davie Ambajilyn (Kamuzu University of Health Sciences, 2020-12-31)

Management of hypertension has challenges due to different factors. These include unavailability of drugs, poor infrastructure, inexperienced personnel, insufficient diagnostic tools, and high treatment costs. Malawi ...
Structure-based in silico identification of novel anticancer natural compounds for enhanced breast cancer chemotherapy

Bvunzawabaya, Jonathan Tatenda (Kamuzu University of Health Sciences, 2022-01-01)

Breast cancer remains a serious public health concern all over the world with heavier burdens on developing countries. In Sub-Saharan Africa, the mortality rate for breast cancer is currently on the rise because of late ...
Development of Loop-mediated Isothermal Amplification (lamp) for detection of macrolide-resistant genes in Streptococcus Pneumoniae

Msefula, Jacquline (Kamuzu University of Health Sciences, 2020-12-01)

Antibiotic resistance is fast becoming a major health problem, which makes it difficult to treat several infections, including Streptococcus pneumoniae infection. Increasing access to antibiotics, presumptive treatment ...
Cardiac disease in children with HIV-associated chronic lung disease at Queen Elizabeth Central Hospital, Blantyre, Malawi

Mapurisa, Gugulethu Newton (Kamuzu University of Health Sciences, 2021-01-01)

Over the past decade, more perinatally-infected children have survived despite previous assertions that few would reach adolescence. More complications of the chronic human immunodeficiency virus (HIV) are surfacing with ...
Association of neonatal hypothermia with morbidity and mortality in a tertiary hospital in Malawi

Phoya, Frank (Kamuzu University of Health Sciences, 2021-11-21)

Neonatal hypothermia is a major risk factor for morbidity and mortality in the first 28 days of life. Studies conducted, in high resource setting have shown the impact of hyperthermia on morbidity and mortality in the first ...
Healthcare-associated urinary tract infection in the Surgery Department at Queen Elizabeth Central Hospital: Deciphering risk factors and antimicrobial resistance patterns of isolated bacteria

Gabriel, Kambale Bunduki (Kamuzu University of Health Sciences, 2021-12-01)

In this dissertation, I investigated the risk factors associated with healthcare-associated infections among patients admitted in surgical wards of the Surgery department of the Queen Elizabeth Central Hospital (QECH), ...
Impact of depression and other common mental disorders on antiretroviral treatment outcomes among Malawian women in the PEPFAR-promote study

Dula, Dingase Elizabeth (Kamuzu University of Health Sciences, 2022-03-01)

Common mental disorders (CMDs) are highly prevalent among people living with HIV(PLWHIV). If left untreated, they negatively affect HIV treatment outcomes. Low cost, low intensity interventions for CMDs such as Friendship ...
The antimicrobial activities of selected local medicinal herbs against Streptococcus pneumoniae

Salifu Mindress, Chifundo (Kamuzu University of Health Sciences, 2021-07-01)

Streptococcus pneumoniae (S. pnuemoniae) is a major cause of invasive pneumococcal infections. Current treatment involves antibiotic therapy and vaccination. The emergence of antibiotic resistance and vaccine serotype ...
Determinants of decisions between clinician and patient to prescribe antimicrobials: A clinician’s perspective

Chalusa, Morris (Kamuzu University of Health Sciences, 2021-10-19)

Antimicrobial resistance is a great public health challenge which has been accelerated by the inappropriate use of antimicrobials. The inappropriate use of antimicrobials is associated with the increased risks of prolonged ...
Emergency care provision and treatment outcomes among under-five children at Mangochi District Hospital

Chinyama, Nitta Beni (Kamuzu University of Health Sciences, 2021-02-01)

WHO/UNICEF developed ETAT guidelines to help improve child survival. Mangochi hospital adopted ETAT in 2009. The hospital’s status of pediatric emergency care was unknown. The aim of the study was to determine characteristics ...
Phytochemical, antioxidant activity and toxicity evaluation of medicinal plants commonly used for asthma management in Malawi

Mwambyale, Tuntufye (Kamuzu University of Health Sciences, 2021-12-01)

Asthma is a chronic disease characterized by recurrent attacks of breathlessness and wheezing, which vary in severity and frequency from person to person. There is minimal scientific research on the efficacy, doses, toxicity ...
Assessing antibiotic prescribing patterns and utilization of microbiological tests results for common bacterial infections in under five inpatients at Ntchisi District Hospital, Malawi

Kondowe, Davie (Kamuzu University of Health Sciences, 2021-04-01)

Antibiotics have remained useful to humans and animals in the treatment of serious infectious diseases for decades now. Unfortunately, irrational antibiotic use has resulted in the emergency of antimicrobial resistance. ...
Comparison of malaria parasite clearance times during Quinine and Artesunate administration for cerebral malaria in Blantyre, Malawi

Saidi, Alexuse Mustaph (Kamuzu University of Health Sciences, 2021-07-01)

Malaria which is caused by Plasmodium species is one of the most important human parasitic diseases. In recent years, preceding 2014, the most severe form of the disease, cerebral malaria, was recommended by World Health ...
Investigation of antimycobacterial and antiviral activities of extracts and compounds isolated from Malawian medicinal plants

Ngonda, Frank Billy Beston (Kamuzu University of Health Sciences, 2020-11-01)

Infectious diseases accounts for approximately one-half of all the deaths that occurs in tropical countries including Malawi. Some of these infectious diseases are caused by microorganism such as mycobacteria and viruses. ...
Assessing the psychological, social and economic effects of caregiving on caregiver of mentally ill older patients accessing services at St John of God Hospital, Mzuzu

Chikopa, Fyness (Kamuzu University of Health Sciences, 2020-12-01)

Currently, in Malawi, there is scarcity of data on studies conducted on the psychological, social and economic effects of caregiving on caregivers of mentally challenged patients, who are also older persons above 60 years ...
Exploring HIV services needs of people at Lilongwe Central Market, Malawi

Jere, James H.C. (Kamuzu University of Health Sciences, 2020-12-01)

Reaching all people with HIV services, including those in the informal economy, is critical to meeting the UNAIDS goals of 95-95-95. However, people who sell in the market, prioritise their business over attendance at ...
Assessment of the effectiveness of health management information system training in Malawi: A case of Lilongwe District

Tambala, Jime Pandor (Kamuzu University of Health Sciences, 2022-03-01)

Health Management Information Systems remains the fundamental systems in the medical sector to support patients’ data and data for decision making. However, despite capacity rendered by different stakeholders to improve ...
Short birth interval and its determinants of reproductive-age women in Ethiopia: Multilevel regression model

Kelel, Henna Umer (Kamuzu University of Health Sciences, 2020-12-01)

A birth interval is the length of time between two successive live births. World Health Organization is recommended that individuals and couples should wait for at least 2–3 years between births to reduce the risk of adverse ...

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